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郭琼玉
副教授
guoqy@sustech.edu.cn

个人简介
郭琼玉,副教授,博士生导师。长期注重于高分子生物材料在转化医学方向的研发,将其应用于多个具有挑战性的生物医学课题,在可移植人工角膜、介入栓塞材料、长效药物控释、记忆性纳米材料以及细胞调控等领域里取得了突出的研究成果。郭琼玉教授是深圳市海外高层次人才“孔雀计划”B类获得者,发表学术论文>40篇,被引用>1200次,申请专利15项,授权11项,其中可移植人工角膜和形状记忆微纳材料的研究成果在全球提交了多项专利申请,已经获得包括中国、美国、日本和欧洲等多个国家的专利授权;撰写专著和章节2部;现任中国医师协会介入医师分会第三届委员会介入医学工程与生物技术学组委员、广东省生物医学工程学会智能介入医学分会常务委员、深圳市生物医学工程学会生物医学材料专业委员会常委。

 

教育背景
2004年-2010年 美国凯斯西储大学高分子工程 博士
1999年-2004年 中国科技大学高分子工程 学士

 

工作经历

2024年5月-至今 南方科技大学生物医学工程系 副教授

2017年-2024年5月  南方科技大学生物医学工程系 助理教授

2016年-2017年 美国里海大学生物工程 研究员
2009年-2016年 美国约翰霍普金斯大学生物医学工程 博士后

 

获奖及荣誉
2010-2013 美国关节炎基金博士后奖学金


研究兴趣
郭琼玉博士主要研究方向是开发纳米至微米尺度新型形状记忆性药物释放体系用于肿瘤治疗和组织再生,其目标为从材料、细胞、动物实验多个层面为解决具体的临床问题设计一系列智能材料。

 

代表论文 
1. Q. Guo, D. Miller, H. An, H. Wang, J. Lopez, D. Lough, L. He and A. Kumar, “Controlled heat stress promotes myofibrillogenesis during myogenesis,” PLoS ONE 11(11) (2016) e0166294.
2. S. Majumdar, Q. Guo, M. Garza-Madrid, X. Calderon-Colon, D. Duan, P. Carbajal, O. Schein, M. Trexler, and J. Elisseeff, “Influence of collagen source on fibrillar architecture and properties of vitrified collagen membranes”, J. Biomed. Mater. Res. Part B. 104B (2016) 300-307.
3. Q Guo, J.P. Mather, P. Yang, M. Boden, and P.T. Mather, “Fabrication of polymeric coatings with controlled microtopographies using an electrospraying technique,” PLoS ONE 10(6) (2015) e0129960.
4. S. Yang,# Q. Guo,# L. Shores, A. Aly, M. Ramakrishnan, G.-H. Kim, Q. Lu, L. Su, G. Zhao, J.H. Elisseeff, “Use of a chondroitin sulfate bioadhesive to enhance integration of bioglass particles for repairing critical-size bone defects,” J. Biomed. Mater. Res. Part A. 103A (2015) 235-242. (#= Co-first author)
5. Q. Guo, J.M. Phillip, S. Majumdar, P. Wu, J. Chen, X. Calderón-Colón, O. Schein, B.J. Smith, M.M. Trexler, D. Wirtz, and J.H. Elisseeff, “Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair,” Biomaterials 34 (2013) 9365-9372.
6. Q. Guo,# X. Wang,# M.W. Tibbitt, K.S. Anseth, D.J. Montell, and J.H. Elisseeff, “Light activated cell migration in synthetic extracellular matrices,” Biomaterials 33 (2012) 8040-8046. (#= Co-first author)
7. Q. Guo, A. Aly, O. Schein, M.M. Trexler, and J.H. Elisseeff, “Moxifloxacin in situ gelling microparticles-bioadhesive delivery system,” Results in Pharma. Sciences 2 (2012) 66-71.
8. A.T. Hillel, S. Unterman, Z. Nahas, B. Reid, J.M. Coburn, J. Axelman, J.J. Chae, Q. Guo, R. Trow, A. Thomas, Z. Hou, S. Lichtsteiner, D. Sutton, C. Matheson, P. Walker, N. David, S. Mori, J.M. Taube, and J.H. Elisseeff, “Photoactivated composite biomaterial for soft tissue restoration in rodents and in human,” Sci. Tranl. Med. 3, 93ra67 (2011) 1-12.
9. Q. Guo, P.T. Knight, J. Wu, and P.T. Mather, “Blends of paclitaxel with POSS-based biodegradable polyurethanes: morphology, miscibility, and specific interactions,” Macromolecules 43 (2010) 4991-4999.
10. Q. Guo, P.T. Knight, and P.T. Mather, “Tailored drug release from biodegradable stent coatings based on hybrid polyurethanes,” J. Control. Release 137 (2009) 224-233.

 

著书章节
1. Q. Guo, and J.H. Elisseeff, Cartilage Tissue Engineering, in: A. Atala, R. Lanza, J.A. Thomson, R. Nerem (Eds.), Principles of Regenerative Medicine, 2nd Ed, Elsevier, 2011, pp. 981-995.

 

专利申请
1. Q. Guo, J. Green, R.A. Meyer, C.J. Bishop, A. Kumar, and G.L. Semenza, “Shape memory particles for biomedical uses,” Patent application (WO2016164458A1) filed on April 6, 2016.
2. A. Kumar, D. Lough, C. Madsen, and Q. Guo, “Bone healing, angiogenesis-promoting and vasculogenesis-producing system,” Patent application (WO2016172004) filed on April 15, 2016.
3. J.H. Elisseeff, Q. Guo, and S. Majumdar, “Compositions comprising cyclodextrin incorporated collagen matrices for use in biomedical applications,” Patent application (US20170043021A1) filed on September 10, 2015.
4. J.H. Elisseeff, Q. Guo, S. Majumdar, and A. Singh, “Cornea mimetic biomaterials: vitrified collagen-cyclodextrin implants,” Patent Application (WO2016171745A1) filed on April 24, 2015.
5. M.M. Trexler, J.H. Elisseeff, D.G. Mulreany, Q. Guo, J.L. Breidenich, J.P. Maranchi, J.L. Graham, J.B. Patrone, M.W. Patchan, and X. Calderon-Colon, “Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof,” Approved by USPTO on April 19, 2016. Patent #US9314531B2.